Scientist Prepared To Take Genes Off For Lesbian Research!



Andrea Burri, MSc of King's College, London, is currently offering to shave her hair, run naked across Westminster Bridge or almost anything else, in order to get donations towards a study into possible connections between genetics and female homosexuality - these desperate measures are a direct result of the difficulties in getting funding from official bodies.  A good looking, queer, Swiss academic, the naked sprint is not an unappealing prospect - one imagines British lesbians forming mobs to donate and spectate.  At this stage, they only have ethical approval to collect samples from volunteers within the UK, although they are very keen to find collaborators and expand into other countries.

Apparently in genetics studies, a homogenous sample is absolutely crucial, due to the differences in the genetic make-up of different races.  Initially, the study will focus on caucasians, for purely practical reasons,  "It's only because of one practical reason: money. To do genetic studies you need to "genotype" the volunteers, which means you draw a kind of a map or a profile of their genes, in order to be able to compare them with each other. Now this is very very cost intensive. Our department has a twin registry of around 10000 twin volunteers out of which around 4000 have already had their "genotyping" (and their all caucasians) therefore it is much cheaper to use these twins who do not consider themselves as being gay as a control group, but to do that you need to compare them to women who consider themselves bisexual or homosexual which are comparable, therefore they need to be caucasian."

Individual volunteers will not have access to their specific results, simply because mapping one person's genome will not produce any information about that person - while as part of a much larger group of people and their genomes, DNA can be compared and results assessed.  The study is also a completely anonymous one, with regards to volunteers and under the auspices of the Ethics Committee, once volunteers have sent in their samples, all of their personal information and contact details are deleted, leaving the sample identified only by an untraceable identification number.

According to Andrea Burri, there has been extensive research into links between genes and male homosexuality, but, "There have been a few very small studies (only about 100-200 sample size) in women. However these studies were really small and had a lot of methodological issues and therefore there results are not really reliable and valid."  There are rumours of a department in the USA intending to conduct a similar study, but the work has not yet begun and so this one's the only one of its size and scope so far worldwide.  On the importance of getting this research off the ground, Andrea says, "Whereas male homosexuality is a well investigated field and a lot of hypotheses and theories have been written, almost nothing is known about female homosexuality when it comes to physiological, biological correlates."

With a pretty comprehensive absence of existing research and results, Andrea says, "We are looking at any random genes that could influence sexual orientation in women. Of course we will have candidates (genes that have been shown to be involved in male homosexuality, sexual orientation etc - if there are any) to start with but basically knowledge is so limited that we would start from 0, and search in a "blind" fashion for what could underly sexual orientation.  We are not interested, or let's say expecting, to find THE gene that makes women gay. It is rather an attempt to explore the genetic basis of sexual orientation in general and many thousands of genes could be involved."

So why has there been research into male homosexuality and the genetic connection and not into the female aspect?  Andrea's theories are both complex and interesting, "First of all, because it seems that there are less taboos in the male gay world compared to female gays and this seems to be true also for research. It looks like gay men are "less" scared to take that step and explore and therefore take more initative to do so.   Secondly, based on research findings so far it seems that female homosexuality is somehow more complex and therefore harder to "assess" given that for example there are many women who consider themselves heterosexual but still have bisexual tendencies. Then again, many women "come out" at a later age, which seems to occur less in gay men ... it seems like there is a bigger heterogeneity in women when it comes to sexual orientation ... and this of course is harder to study." 

As for her own personal interest in the field, "Ah you know when you got ten research papers lying in front of you and you always go for the sex stuff instead of things like depression or phobias then somehow the decision is already made!"

Wanna get involved
 

Melanie Lowe Speaks Out About Coming Out

June 19, 2009


Melanie Lowe ... the spiky haired girl we all speculated about on the first series of South African Idols, the one whose (male) fiancé didn't stop us speculating, finally came out of the closet in June's O Magazine - a skillful way to let the world at large know something that we, the queer community, have been widely aware of for years now.  South Africa's LGBTQ community is a relatively small one and a lot of it is in the closet due to cultural taboo - corrective rape within some segments ...

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The Taiwanese Lesbian Scene: Tomboy & Pao

March 29, 2009
I got talking to Andrea Toerien - a friend of mine in Taiwan, who also happens to be a lesbian.  She told me about T's and P's; Tomboys and Pao (wives) and showed me photographs and immediately it was apparent that the Taiwanese scene is rather different to the Western butch/femme dynamic - for one thing, they're more scene, theme and appearance conscious than most of us can imagine.



So tomboys don't go out with tomboys and pao don't go out with pao?  Usually not. There are a few couples tha...

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Deb Adler - cool and old skool

March 2, 2009

By Ulla Kelly

Deb Adler has been entertaining diverse audiences professionally for over forty years. Trained in both music and theater, Deb's performance background includes everything from glee clubs, choruses, and classical choral unions, to folk groups, to solo performances.

You've been out and singing about it for a long time now – what are the biggest changes you've noticed?
Definitely the integration into mainstream. When I started performing as a "Lesbian-feminist singer-songwriter...


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Karma: Comfort & Confusion

February 28, 2009

With her new CD, “Papercuts” coming out in South Africa at the end of the month, it seemed like a great time to talk to Karma; a firm favourite amongst South Africans since the nineties and Henry Ate.  I asked her about American things, South African things, queer things - and things about how she writes the kind of songs that stick in your heart and mind forever.  Unfortunately, I completely forgot to ask her how many of her fans are Buddhist.  2008 has seen her play on three continents ...


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Drag is a Verb Too

February 28, 2009
23 10 2008
HRH Nomi Perron
HRH Nomi Perron

Drag queens make me think of disco balls rotating lazily, filling rooms with sparkles.  They make me think of high heels, lipstick, cabaret and beautiful, brave people.  The general preconception is that they’re all wannabe women, as camp as a row of pink tents.  Until I photographed drag queens at Joburg Pride recently, I’ve never had much personal contact with them at all, apart from the odd giggle together at a gay...


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Melanie Lowe

February 28, 2009
24 10 2008
Melanie Lowe
Melanie Lowe

Gay men always comment on my shoes! And gay women … well, I’ll leave you to decide what it is they comment on.

From her funky, vibrant presence on Idols all those years ago, to today’s more sultry woman, Melanie Lowe has paid her dues on the South African music scene.  She handles her own career and like many artists these days, is utilising social networking tools such as Myspace and Facebook to stay close to her fans...


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When America Laughs - an Interview with Kate Clinton

February 28, 2009

She calls herself a fumerist (feminist humourist)  - Kate Clinton; stylish butch and one of the funniest lesbians in the USA  And for fellow South Africans who may not know much about her, the good news is that there’s plenty out there to get your grubby little cyber paws on.  She blogs all over the place and there’s lots of video too.  her live performances are legendary, her DVD’s are hysterical and she’s been in the comedy game for 25 years.   When...


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Keeping Up With The Stealing Love Joneses

February 28, 2009

scott graham

photo: scott graham

I’ve seen Stealing Love Jones play live a good few times, to big crowds and small.  I even saw Esjay do an acoustic set once.  I’ve also seen her play at lesbian events and she was not only truly cool and comfortable with it, but pretty flirtatious with the crowd too.  The music is fabulous - slightly offbeat, but mostly damn good rawwwk.  Esjay is one of those people who seems to have been born and bred for stardom.  She’s a natural; she’s straightforward, in-yer...


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Shooting the Breeze with Michelle Breeze of Darkpop

February 28, 2009
I found Michelle by surfing along to www.darkpop.co.uk where I saw that Darkpop made the site themselves, and that it’s the only way to get your sticky paws on their exceedingly sublime album ‘Golden Lillies + Mr Smith.’ If you have a look at the Biography link, you’ll see that the mesmerising vocalist is our very own Michelle Breeze, of Fetish fame. There’s an intriguing remark on the website’s front page too, “We know that we are definitely not cool, therefore your love is all...

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Got something subcultural (heh!) to share?  Use the contact page and let me know - if it's interesting, your interview might just appear here and on a website or two that I write for. 

Most interviews here appeared on queerlife.co.za with the exception of The World Unseen, which was commissioned by mambagirl.com.  Some interviews have been republished on cherrygrrl.com

All interviews from the March 29th one onwards are up for grabs - use the contact form to liaise.

Great news, my interview with The World Unseen people was the cover story of the South African Big Issue March 6 2009.